Kupanga Zoweruza (Ma Antibodies, Ma cell Therapies)
Malo apamwamba kwambiri a cGMP antibody ndi cell therapy omwe ali ku San Diego, CA, omwe poyamba adapangidwa kuti akhale malo opangira zinthu zambiri zopangira mapuloteni oyeretsedwa kwambiri ndi ma antibodies kuti azigwiritsidwa ntchito ngati mankhwala. Malo okonzedwanso amakwaniritsa zofunikira za cGMP zopangira Investigational New Drugs, ndipo tsopano zikuphatikiza kuthekera kwamankhwala amafoni.
Kudzaza kwa Bioserv Aseptic ndikumaliza Malo Opangira Makontrakitala
Tsopano gawo lamphamvu za Sorrento, Bioserv, bungwe la cGMP lopanga ma contract lidapezedwa ndikuphatikizidwa. Ndi malo/zipinda zoyeretsera ndi makina okhwima okhwima, Bioserv imapereka ntchito za aseptic komanso osagwiritsa ntchitoaseptic kudzaza/kumaliza kuphatikiza lyophilization ya biotechnology, mafakitale opanga mankhwala ndi matenda, komanso kulemba zilembo / zida ndi kutentha kwanthawi yayitali, kuzizira komanso kuzizira.
Camino Santa Fe Oncolytic Virus Production Facility
Malo opangira ma virus ku Sorrento akuphatikiza kukonza njira ndi ma labotale owunikira komanso zipinda zoyera za cGMP. Ntchito zomwe zimathandizidwa zikuphatikiza chikhalidwe cha ma cell, kuyeretsa, kudzaza ndi kutsiriza njira komanso kakulidwe ka ma analytics ndi kuyesa kuwongolera khalidwe. Malowa ali ndi chilolezo ndi CA Food and Drug Branch ndipo apanga bwino zinthu za mankhwala ndi mankhwala osokoneza bongo kuti ayambe kuyesa kuchipatala, PHASE I ndi PHASE II.
ADC Conjugation, Payload ndi Linker Synthesis Facility
Sorrento imagwiritsa ntchito cGMP yake yopanga Antibody Drug Conjugate (ADC) ku Suzhou, China, pansi pa dzina la Levena Biopharma. Tsambali lakhala likugwira ntchito kuyambira chaka cha 2016 ndipo limatha kuthandizira kupanga cGMP yamankhwala olumikizirana ndi mankhwala komanso kulumikizana kwa antibody. Ndi mphamvu zowunikira zonse komanso malo okhala ndi zida zamphamvu kwambiri za API (odzipatula), tsambali lathandizira magulu opitilira 20 azachipatala padziko lonse lapansi.
Sofusa Research and Production Facility
Kuthekera kopanga SOFUSA ku Atlanta, GA kumaphatikizapo njira zolondola za nanofabrication pamodzi ndi kusonkhanitsa ndi kuyesa zida zazida. Opaleshoniyo imatha kuthandizira kupanga zida zodziwikiratu kuti zithandizire maphunziro a preclinical komanso mayeso achipatala a Phase I ndi II. Kuphatikiza apo, malo ofufuzira a SOFUSA ndi labu yaying'ono yogwira ntchito mokwanira yokhala ndi luso lamakono lojambula (NIRF, IVIS, PET-CT) kuti liwonetsere bwino momwe ma lymphatic amakhudzidwira ndi jakisoni wamba ndi kulowetsedwa.
