“Sorrento antibody library was constructed using proprietary G-MAB™ Technology. It is one of the largest and most diverse libraries of fully human antibodies in the biopharmaceutical industry.” Dr. Henry Ji, CEO
G-MAB Library Technology
Sorrento’s proprietary G-MAB technology, invented by Dr. Ji, is based on the use of RNA transcription for amplification of the antibody variable regions of over 600 healthy donors. In-depth analysis of deep sequencing DNA data showed that the G-MAB library contains more than 10 quadrillion (1016) distinct antibody sequences. This makes it one of the largest fully human antibody libraries in the biopharmaceutical industry. Thus far, Sorrento Therapeutics has successfully identified fully human antibodies against over 100 clinically-relevant targets from its G-MAB library. The lead therapeutic antibody programs will enter human trials in 2016.