I Sofusa® I-Lymphatic Delivery System (S-LDS) yindlela entsha yonyango eyilelwe ukuhambisa amayeza atofwayo ngokuthe ngqo kwi-lymphatic kunye ne-systemic capillaries nje ngaphantsi kwe-epidermis ngokusebenzisa i-microneedle yobunikazi kunye nenkqubo ye-microfluidics.
Inkqubo yokuhanjiswa kweSofusa Lymphatic isishwankathelo. Tyelela www.sofusa.com »
Ukufunxa okongeziweyo
Ngokungafaniyo nanaliti zemveli, inkqubo ye-Sofusa ("i-soft transdermal infusion) yenza ukuba kufakwe ukulawulwa kwi-lymphatic kunye ne-systemic capillaries nje ngaphantsi kwe-epidermis.
INanotopography (yandiswe kakhulu)
Ubunikazi befilimu ebhityileyo i-nanotopography esetyenziswa kwii-microneedles ikhokelela ekonyukeni okumangalisayo kokufunxa iimolekyuli ezinkulu vs ii-microneedles ezingafakwanga.
Ukujoliswa kwe-Intra-Lymphatic
Kwiimodeli zangaphambi kweklinikhi xa kuthelekiswa nenaliti yesintu, iSofusa ibonakalise impendulo ephuculweyo yeklinikhi ngokunyuka kokugxila kwi-lymphatic kunye nokuncipha kokuvezwa kwenkqubo.1.
(1) Idatha kwifayile-Izifundo ezininzi zangaphambi kweklinikhi ezibandakanya i-etanercept, trastuzumab, CTLA-4, PD-1, kunye nePD-L1