Ukwenziwa kweJudicial (Antibodies, uNyango lweSeli)
I-antibody ye-cGMP ye-state-of-the-art kunye nendawo yokuvelisa unyango lweeseli e-San Diego, CA, ekuqaleni yayiyilwe ukuba ibe yindawo yemveliso emininzi yokwenziwa kweeprotheyini ezihlambulukileyo kunye nezilwa-buhlungu ezisetyenziselwa ukusetyenziswa njengonyango. Indawo eyilwe ngokutsha ihlangabezana neemfuno ezisebenzayo ze-cGMP zokwenziwa koPhando lwaMachiza amatsha, kwaye ngoku ibandakanya izakhono zonyango lweselula.
I-Bioserv Aseptic Gcwalisa kwaye ugqibezele iZiko lokuVelisa ikhontrakthi
Ngoku inxalenye yezakhono ezingundoqo ze-Sorrento, i-Bioserv, i-cGMP intlangano yenkonzo yokwenziwa kwekhontrakthi yafunyanwa kwaye yadityaniswa. Ngamaziko / amagumbi okucoca kunye neenkqubo ezisemgangathweni ezivuthiweyo, i-Bioserv ibonelela ngeenkonzo ze-aseptic kunye ne-non-aseptic yokuzalisa / yokugqiba kuquka i-lyophilization ye-biotechnology, amashishini amayeza kunye nokuxilongwa, kunye nokubhala / ukubethelwa kunye nokushisa kwexesha elide elilawulwayo, ukugcinwa okubandayo kunye nomkhenkce.
Camino Santa Fe Oncolytic Virus Production Facility
Indawo yokuvelisa intsholongwane egazini yaseSorrento ibandakanya uphuhliso lwenkqubo kunye neelebhu zovavanyo lohlalutyo kunye namagumbi acocekileyo e-cGMP. Imisebenzi exhaswayo ibandakanya inkcubeko yeeseli, ukuhlanjululwa, ukuzalisa kunye nokugqiba iinkqubo kunye nophuhliso lovavanyo lohlalutyo kunye novavanyo lokulawula umgangatho. Eli ziko linikwe ilayisenisi yi-CA Food and Drug Branch kwaye lenze ngempumelelo amachiza kunye neemveliso zamachiza ukulungiselela ulingo lwaphambi koklinikhi, ISIGABA soku-I kunye nesiGaba sesi-II.
I-ADC Conjugation, Payload and Linker Synthesis Facility
I-Sorrento isebenzisa indawo yayo ye-cGMP yemveliso ye-Antibody Drug Conjugate (ADC) e-Suzhou, e-China, phantsi kwegama le-brand ye-Levena Biopharma. Indawo ibisebenza ukusukela ngo-2016 kwaye inokuxhasa ukuveliswa kwe-cGMP yeklinikhi yabanxibelelanisi bamachiza kunye nokudibanisa i-antibody. Ngobuchule obupheleleyo benkxaso yohlalutyo kunye nesibonelelo esixhotyiselwe ukuphatha i-API enamandla kakhulu (isolator), indawo iye yaxhasa ngaphezu kweebhetshi zeklinikhi ezingama-20 kulingo lwezonyango kwihlabathi liphela.
Uphando lweSofusa kunye neZiko lokuVelisa
I-SOFUSA yokuvelisa amandla e-Atlanta, GA ibandakanya ukuchaneka kobuchule bokwenza i-nanofabrication ecaleni kwendibano kunye novavanyo lwamacandelo esixhobo. Umsebenzi uyakwazi ukuxhasa ukwenziwa kwezixhobo zesiqhelo ukuxhasa izifundo zaphambi kweklinikhi kunye neSigaba soku-I nesesi-II solingo lwezonyango. Ukongeza, iziko lophando le-SOFUSA liyilebhu yezilwanyana ezincinci ezisebenza ngokupheleleyo kunye ne-state-of-the-art i-imaging capabilities (NIRF, IVIS, PET-CT) ukubonisa ngokupheleleyo impembelelo yokuhanjiswa kwe-lymphatic ngokubhekiselele kwiinaliti zendabuko kunye nokufakwa.
