SOFUSA Platform Gudbinta Daawooyinka Lymphatic
Sofusa® Nidaamka Bixinta Lymphatic (S-LDS) waa hab cusub oo daaweyn ah oo loogu talagalay in lagu gaarsiiyo daawooyinka la isku duro si toos ah lymfatic iyo capillaries nidaamsan oo ka hooseeya epidermis iyada oo loo marayo microneedle iyo nidaamka microfluidics.
Nidaamka Bixinta Lymphatic Sofusa Guudmarka. Booqasho www.sofusa.com
Moodooyinka hore ee kiliinikada waxay muujinayaan faa'iidooyinka suurtagalka ah ee bartilmaameedsiga lymfatic ee leh Sofusa nano-dabiran microneedles1
- > 40-laab korodhka fiirsashada daroogada ee qanjidhada iyo irbadaha subcutaneous (SC) ama faleebooyinka xididka (IV)
- Galitaanka burada oo la hagaajiyay 1/10th qiyaas
- Waxtarka ka hortagga burooyinka oo la hagaajiyay iyo hoos u dhaca metastases
Daraasaadka Kiliinikada Aadanaha ee Wajiga 1B RA si loo qiimeeyo dhalmada gudaha-lymphatic2
- Daraasad summadeed furan oo 12-usbuuc ah oo diiwaan-gelinaysa bukaannada aan haysan jawaab-celin ku filan 50mg toddobaadle Enbrel® cirbadaha subcutaneous (n=10)
- Bukaannada 3 ee ugu horreeya waa la dhammaystiray, 25mg toddobaadle ah (50% qiyaasta SC)
- 36%/38% hoos u dhaca Hawlaha Cudurada (DAS28 ESR/CRP)
- 80% hoos u dhaca kala goysyada bararka
- Horumarka 77% ee Dhibcaha Qiimaynta Caalamiga ah ee Dhakhtarka
Barta-baarinta bini'aadamka ee POC waxay ka socotaa Mayo Clinic
1) Walsh et al., "Nanotopography wuxuu fududeeyaa gaarsiinta Vivo Transdermal… Nano Warqadaha, ACSJCA, 2015
2) Natiijooyinku waa celceliska bukaannada 3 ee ugu horreeya (qayb qayb ka diiwaangashan), Wajiga 1b caddaynta fikradda daraasadda sumadda furan si loo qiimeeyo badbaadada iyo waxtarka tijaabada ee Enbrel® ee lagu maamulo bukaannada qaba Rheumatoid arthritis iyadoo la adeegsanayo Sofusa® DoseConnct®