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Timagwiritsa ntchito sayansi yotsogola kuti tipange njira zochiritsira zatsopano zomwe zingasinthe miyoyo ya iwo omwe akudwala khansa, ululu wosachiritsika ndi COVID-19.

Cancer ndi mitundu yosiyanasiyana, yosinthika kwambiri, yosinthika nthawi zonse komanso yosawoneka ndi chitetezo chamthupi. Njira yathu yochizira khansa imachokera ku chikhulupiliro chakuti odwala adzafunika njira zambiri, zowonjezereka - kutsata ndondomeko imodzi kapena yosiyana-siyana ya ma cell ndikuwukira omwe ali pazigawo zingapo - panthawi imodzi kapena motsatizana, kawirikawiri komanso mosalekeza.

Njira yathu yothanirana ndi khansa imatheka chifukwa cha gulu lapadera la immuno-oncology ("IO"), lomwe lili ndi zida zambiri zaluso komanso zogwirizana, monga laibulale yayikulu ya antibody ("G-MAB™") yomwe imatha kugwiritsidwa ntchito paokha kapena kuphatikizidwa munjira zolimbana ndi khansa kuphatikiza:

Katunduyu amathandizidwa ndi chipangizo chatsopano cholozera ma lymphatic (Sofusa®) opangidwa kuti apereke ma antibodies mu lymphatic system, momwe maselo oteteza thupi amaphunzitsidwa kulimbana ndi khansa. 

Tapanga ma antibodies a anthu motsutsana ndi mipherezero yambiri yofunikira pakuchiza khansa, kuphatikiza PD-1, PD-L1, CD38, CD123, CD47, c-MET, VEGFR2, ndi mipherezero ina yambiri, yomwe ili pamagawo osiyanasiyana achitukuko. Mapulogalamu athu a CAR-T akuphatikiza gawo lachipatala la CD38 CAR T. Njira zochiritsira zomwe zimaphatikiza njira ndizomwe zimawunikiridwa bwino za myeloma yambiri, khansa ya m'mapapo, ndi khansa ina ya akulu ndi ana.

  • CAR T (Chimeric Antigen Receptor - T Cells) therapy yomwe imasintha ma T-cell a wodwala kuti aphe chotupa chake.
  • Thandizo la DAR T (Dimeric Antigen Receptor - T Cells) lomwe limasintha ma T-cell a wopereka wathanzi kuti azigwira ntchito ku chotupa cha wodwala aliyense, ndikulola "kuchotsa shelufu" chithandizo cha chotupa cha wodwala.
  • Antibody-Drug Conjugates ("ADCs"), ndi
  • Mapulogalamu a Oncolytic Virus (Seprehvir™, Seprehvec™)

"Ntchito zathu zapadera za IO papulatifomu sizingafanane ndi malonda. Mulinso ma immune checkpoint inhibitors, ma bispecific antibodies, antibody-drug conjugates (ADCs) komanso chimeric antigen receptor (CAR) ndi dimeric antigen receptor (DAR) based cellular therapies, ndipo posachedwa tawonjezera ma virus a oncolytic (Seprehvir™, Seprehvec). ™). Katundu aliyense payekha amawonetsa lonjezo lalikulu; pamodzi tikuwona kuti ali ndi kuthekera kothana ndi zovuta zovuta za khansa "

- Dr. Henry Ji, CEO

Kudzipereka kwathu pakupititsa patsogolo miyoyo ya odwala omwe panopa akuganiziridwa kuti ndi ululu wosasunthika kumasonyezedwanso ndi khama lathu lokhala ndi gawo loyamba (TRPV1 agonist) lopanda opioid, Resiniferatoxin ("RTX").

Resiniferatoxin imatha kusintha kwambiri njira yothetsera ululu mu zizindikiro zosiyanasiyana, chifukwa cha mphamvu yamphamvu komanso yokhalitsa ndi kayendetsedwe kamodzi komanso chifukwa cha ubwino wa mbiri yake yopanda opioid.

RTX ikumaliza mayeso ofunikira kwambiri pazowonetsa anthu monga osteoarthritis komanso kutha kwa ululu wa khansa ya moyo, ndi maphunziro ofunikira olembetsa omwe akuyembekezeka kuyambitsa theka lachiwiri la 2020.

RTX ilinso m'mayesero ofunikira kuti agwiritse ntchito agalu omwe ali ndi vuto lothana ndi ululu wa nyamakazi. Monga ziweto zili mbali ya banja, njira yathu yopangira njira zothetsera ululu imayenera kuphatikizapo mitundu ina yomwe timakonda!