ACEA Therapeutics

ACEA Therapeutics, yomwe ili ku San Diego, California ndi gulu lathunthu la Sorrento. ACEA Therapeutics yadzipereka kupanga ndikupereka chithandizo chamakono kuti chitukule miyoyo ya odwala omwe ali ndi matenda oopsa.

Gulu lathu lotsogolera, Abivertinib, kakang'ono ka molekyulu kinase inhibitor, pano likuwunikiridwa ndi China Food and Drug Administration (CFDA) pochiza odwala omwe ali ndi khansa ya m'mapapo yopanda yaying'ono (NSCLC) yomwe ili ndi kusintha kwa EGFR T790M. Zilinso m'mayesero azachipatala ochiza odwala omwe ali m'chipatala omwe ali ndi Covid-19 ku Brazil ndi US motsogozedwa ndi Sorrento Therapeutics. Kachilombo kakang'ono ka molecule kinase inhibitor ya ACEA, AC0058, yalowa mu Phase 1B chitukuko ku US pochiza systemic lupus erythematosus (SLE).

Pamodzi ndi bungwe lolimba la R&D, ACEA yakhazikitsa luso lopanga mankhwala ndi malonda ku China kuti zithandizire kukula kwathu kwanthawi yayitali. Zomangamangazi zimatipatsa mphamvu zoyendetsera ntchito yathu kuti titsimikizire kuti zinthu zimaperekedwa kwa odwala panthawi yake.

Chithunzi cha SCILEX

SCILEX HOLDING COMPANY ("Scilex") , gulu lothandizira ambiri la Sorrento, likudzipereka pa chitukuko ndi malonda a mankhwala opweteka. Zogulitsa zotsogola zamakampani ZTlido^® (lidocaine topical system 1.8%), ndi mankhwala amtundu wa lidocaine apamutu omwe amavomerezedwa ndi US Food and Drug Administration kuti athetse ululu wokhudzana ndi Post-Herpetic Neuralgia (PHN), womwe ndi mtundu wa ululu wa mitsempha ya post-shingles.

Scilex's SP-102 (10 mg dexamethasone sodium phosphate gel), kapena SEMDEXA™, pochiza Lumbar Radicular Pain ali mkati momaliza kuyesa kwachipatala kwa Phase III. Kampaniyo ikuyembekeza kuti SP-102 ikhale jakisoni woyamba wa FDA wovomerezeka kuti athetse ululu wa lumbosacral radicular, kapena sciatica, wokhala ndi mwayi wosintha majekeseni a 10 mpaka 11 miliyoni a epidural steroid omwe amaperekedwa chaka chilichonse ku US.

Bioserv

Bioserv, yomwe ili ku San Diego, California ndi gulu lathunthu la Sorrento. Lakhazikitsidwa mu 1988, bungweli ndi mtsogoleri wotsogola wopanga mgwirizano wa cGMP wokhala ndi malo opitilira masikweya 35,000 omwe luso lawo lalikulu limakhazikika pamapangidwe ambiri a aseptic ndi non-aseptic; kusefa; kudzaza; kuyimitsa; ntchito za lyophilization; kulemba; kukonza zinthu zomalizidwa; kitting ndi kulongedza; komanso ntchito zowongolera kutentha kwa kutentha ndi ntchito zogawa kuti zithandizire Pre-Clinical, Phase I ndi II Clinical Trial mankhwala mankhwala, reagents zipangizo zachipatala, reagents Medical diagnostic reagents ndi kits, ndi moyo sayansi reagents.

Concortis-Levena

Mu 2008, Concortis Biosystems idakhazikitsidwa ndi cholinga chotumikira bwino gulu la sayansi ndi mankhwala okhala ndi zida zapamwamba kwambiri za antibody drug conjugate (ADC) ndi ntchito. Mu 2013, Sorrento adapeza Concortis, ndikupanga kampani yapamwamba ya ADC. Kuphatikiza kwa G-MAB™ (laibulale ya antibody yathunthu) yokhala ndi poizoni wa Concortis, zolumikizira, ndi njira zolumikizira zimatha kupanga ma ADC otsogola kumakampani, a 3rd m'badwo.

Concortis pakali pano ikuyang'ana njira zopitilira 20 za ADC (zachipatala) zomwe zimagwiritsidwa ntchito mu oncology ndi kupitilira apo. Pa Okutobala 19, 2015, Sorrento adalengeza kukhazikitsidwa kwa Levena Biopharma ngati bungwe lodziyimira palokha kuti lipereke msika wamitundumitundu yantchito za ADC kuyambira kukhazikitsidwa kwa projekiti ya ADC kudzera mu cGMP kupanga ma ADC mpaka gawo la I/II lachipatala. Kuti mudziwe zambiri, chonde pitani www.levenabiopharma.com

Malingaliro a kampani SmartPharm Therapeutics, Inc

SmartPharm Therapeutics, Inc. ("SmartPharm"), kampani yocheperako ya Sorrento Therapeutics, Inc. (Nasdaq: SRNE), ndi kampani yopanga mankhwala a biopharmaceutical yomwe imayang'ana kwambiri m'badwo wotsatira, mankhwala osagwiritsa ntchito ma virus pochiza matenda oopsa kapena osowa ndi masomphenya opanga "biologics mkati." SmartPharm pakadali pano ikupanga buku, DNA-encoded monoclonal antibody kuteteza matenda a SARS-CoV-2, kachilombo komwe kamayambitsa COVID-19 pansi pa mgwirizano ndi Defense Advanced Research Projects Agency ku US Department of Defense. SmartPharm idayamba kugwira ntchito mu 2018 ndipo ili ku Cambridge, MA, USA.

Ark Animal Health

Ark Animal Health ndi gawo lathunthu la Sorrento. Ark idapangidwa mu 2014 kuti ibweretse mayankho amsika amsika amsika omwe amachokera ku kafukufuku wa anthu a Sorrento ndi chitukuko. Ikukonzedwa kuti ikhale bungwe lodziyimira palokha komanso lodzidalira likafika pagawo lazamalonda (zogulitsa zokonzeka kulandira chivomerezo cha FDA).

Ark's lead development program (ARK-001) ndi mulingo umodzi wa resiniferatoxin (RTX) wosabala jekeseni yankho. ARK-001 yalandira FDA CVM (Center for Veterinary Medicine) MUMS (yogwiritsa ntchito yaying'ono/mitundu yaying'ono) yowongolera ululu wa khansa ya mafupa mwa agalu. Ntchito zina zikuphatikizapo zisonyezo zowonjezera za RTX m'madera monga kupweteka kosalekeza kwa nyama zina, ululu wa neuropathic mu akavalo, ndi idiopathic cystitis mu amphaka, komanso kufufuza mwayi wa chitukuko m'dera la matenda opatsirana kapena chithandizo cha khansa.

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