DAR T (Dimeric Antigen Receptor-T Cell)

Ka whakamahi a Sorrento i te hangarau patoto-ki-roto (KOKI) ki te whakarereke i nga pūtau T i ahu mai i te kaihaoha hauora hei hanga ira ki te whakaputa i te kaikawe antigen dimeric ki roto i te rohe mau tonu o te mekameka alpha (TRAC). Ma tenei tikanga, ka turakihia a TRAC ka patotohia te antigen ki tona waahi. 

Ka whakamahia e te Dimeric Antigen Receptor (DAR) he Fab hei utu mo te scFv e whakamahia ana e nga pūtau T Chimeric Antigen Receptor (CAR) tuku iho. E whakapono ana matou kua whakaatuhia tenei DAR i roto i nga rangahau preclinical te tino motuhake, te pumau me te kaha.