Cov kab mob Oncolytic (Seprehvir™, Seprehvec™)

Sorrento's oncolytic viral vector cov cuab tam yog ib qho kev hloov kho ntawm tib neeg tus kab mob herpes simplex (HSV-1). Seprehvir tau raug tsim los nrog lub peev xwm tshwj xeeb los rhuav tshem cov qog hlwb thaum tseem txhawb nqa cov qog nqaij hlav tiv thaiv kab mob. Raws li ib feem ntawm nws txoj kev kho mob thoob ntiaj teb, Seprehvir tau muab tshuaj rau ntau tshaj 100 tus neeg laus thiab cov neeg mob hauv ntau hom qog nqaij hlav xws li glioblastoma, mesothelioma, melanoma, mob qog noj ntshav taub hau thiab caj dab, mob qog noj ntshav thiab menyuam yaus neuroblastomas.

Ib qho txiaj ntsig tseem ceeb ntawm Seprehvir, piv rau lwm cov kev kho mob HSV-based oncolytic, yog tias nws tau txais kev nyab xeeb ntawm kev siv tshuaj intravenously, intratumorally thiab los ntawm loco-regional infusion rau tshwj xeeb kho kho rau tus neeg mob qog noj ntshav.

Cov cuab tam Seprehvec yog ib txoj haujlwm tiam tom ntej uas lub hom phiaj muab kev kho mob ntxiv thiab tuaj yeem tsim cov tshuaj tiv thaiv kab mob oncolytic sai sai:

• "Targeted" tshwj xeeb rau qee hom qog hlwb
• "Armed" nrog cov noob ntxiv los txhim kho kev puas tsuaj ntawm cov qog hlwb
• Multi-functional "targeted" thiab "armed" variants nrog txhim kho cell tua thiab immuno-stimulatory kev ua ub no