ADCs

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ADC (Antibody Drug Conjugates)

Antibody Drug Conjugates (ADC)

Antibody-drug conjugates (ADCs) yog lub hom phiaj tiv thaiv kab mob uas siv cov tshuaj muaj zog cytotoxic conjugated rau cov tshuaj tiv thaiv los ntawm cov tshuaj txuas. Qhov no ua rau muaj kev ua tau zoo ntawm cov tshuaj chemotherapeutic los ntawm kev tsom cov tshuaj ncaj qha rau cov qog nqaij hlav cancer. Yog li, ADCs kuj tau txo cov kev mob tshwm sim vim kev tsom mus rau cov qog nqaij hlav cancer txhais tau tias tsawg dua ntawm cov tshuaj cytotoxic yuav nkag mus rau cov hlwb noj qab haus huv.

Sorrento tiam tom ntej ADC thev naus laus zis platform siv cov txheej txheem sib txuas tshiab los tsim cov ADCs ruaj khov los ntawm kev txuas cov tshuaj lom mus rau qhov tshwj xeeb, xaiv qhov chaw ntawm cov tshuaj tiv thaiv kab mob; Qhov tshwm sim ADCs tau pom tias muaj kev tiv thaiv qog noj ntshav hauv cov kev tshawb fawb ua ntej.

ADC thev naus laus zis siv cov cuab yeej sib txuas ua ke (C-Lock ™ thiab K-Lock ™), pib tsim los ntawm Concortis Biosystems, Corp.

Kev sib xyaw ua ke ntawm C-Lock thiab K-Lock conjugation txoj kev ua rau muaj ntau yam ADCs, xws li ob hom tshuaj ADCs thiab Bispecific ADCs. Peb kuj tseem nquag kawm txog kev sib xyaw ntawm ADCs nrog kev tiv thaiv kab mob oncology raws li lub tswv yim tshiab los tiv thaiv qog noj ntshav.

Peb tab tom tsim ADCs tsom rau CD38 thiab BCMA.