ACEA Kev Kho Mob

ACEA Therapeutics, nyob hauv San Diego, California yog ib lub koom haum ua lag luam ntawm Sorrento. ACEA Therapeutics tau cog lus los tsim thiab xa cov kev kho tshiab los txhim kho lub neej ntawm cov neeg mob uas muaj kab mob ua rau lub neej.

Peb cov hlau lead compound, Abivertinib, me me molecule kinase inhibitor, tam sim no nyob rau hauv kev tshuaj xyuas los ntawm Tuam Tshoj Food and Drug Administration (CFDA) rau kev kho mob ntawm cov neeg mob uas tsis yog-me me cell ntsws cancer (NSCLC) uas muaj EGFR T790M kev hloov. Nws kuj tseem nyob hauv kev sim tshuaj kho mob rau cov neeg mob hauv tsev kho mob nrog Covid-19 hauv Brazil thiab Asmeskas coj los ntawm Sorrento Therapeutics. Ib qho thib ob me me molecule kinase inhibitor ntawm ACEA, AC0058, tau nkag mus rau theem 1B kev loj hlob hauv Asmeskas rau kev kho mob ntawm cov kab mob lupus erythematosus (SLE).

Nrog rau lub koom haum R & D muaj zog, ACEA tau tsim kev tsim tshuaj thiab kev lag luam muaj peev xwm hauv Suav teb los txhawb peb txoj kev loj hlob mus ntev. Qhov kev tsim kho vaj tse no muab kev tswj xyuas ntau dua rau peb cov saw hlau xa khoom kom paub tseeb tias cov khoom xa tuaj rau cov neeg mob raws sijhawm.

SCILEX

SCILEX HOLDING COMPANY ("Scilex"), ib lub tuam txhab ua lag luam feem ntau ntawm Sorrento, tau mob siab rau kev txhim kho thiab kev lag luam ntawm cov khoom tswj kev mob. Lub tuam txhab ua cov khoom lag luam ZTlido^® (lidocaine topical system 1.8%), yog ib hom tshuaj lidocaine tshuaj pleev ib ce uas tau pom zoo los ntawm US Food and Drug Administration rau kev kho mob ntawm Post-Herpetic Neuralgia (PHN), uas yog ib daim ntawv ntawm post-shingles paj paj.

Scilex's SP-102 (10 mg dexamethasone sodium phosphate gel), los yog SEMDEXA ™, rau kev kho mob ntawm Lumbar Radicular Pain yog nyob rau hauv tus txheej txheem ntawm ua kom tiav Phase III kev kuaj mob. Lub tuam txhab cia siab tias SP-102 yuav yog thawj FDA pom zoo tsis-opioid epidural txhaj tshuaj los kho lumbosacral radicular mob, los yog sciatica, nrog lub peev xwm los hloov 10 mus rau 11 lab off-label epidural steroid txhaj tshuaj txhua xyoo hauv Teb Chaws Asmeskas.

Bioserv

Bioserv, nyob hauv San Diego, California yog ib lub koom haum ua lag luam ntawm Sorrento. Founded hauv 1988, lub koom haum yog ib tug thawj coj cGMP daim ntawv cog lus muab kev pab cuam muab kev pab cuam nrog ntau tshaj 35,000 square feet ntawm cov chaw uas nws muaj peev xwm tseem ceeb nyob rau hauv aseptic thiab non-aseptic bulk formulation; lim; filling; nres; kev pabcuam lyophilization; daim ntawv lo; Cov khoom tiav ua ke; kitting thiab ntim khoom; nrog rau kev tswj xyuas qhov kub thiab txias cov kev pab cuam los pab txhawb Pre-Clinical, Phase I thiab II Clinical Trial cov khoom siv, cov cuab yeej siv kho mob, cov khoom siv kho mob thiab cov khoom siv kho mob, thiab cov khoom siv hauv lub neej.

Concortis-Levena: koj puas xav tau ntau tus thwjtim?

Hauv xyoo 2008, Concortis Biosystems tau tsim nrog lub hom phiaj kom ua haujlwm zoo dua rau kev tshawb fawb thiab tshuaj hauv zej zog nrog cov tshuaj tiv thaiv kab mob zoo (ADC) reagents thiab cov kev pabcuam. Xyoo 2013, Sorrento tau txais Concortis, tsim lub tuam txhab ADC sab saum toj. Kev sib xyaw ua ke ntawm G-MAB ™ (tag nrho tib neeg cov tshuaj tiv thaiv lub tsev qiv ntawv) nrog Concortis proprietary co toxins, linkers, thiab conjugation txoj kev muaj peev xwm los tsim kev lag luam-kev ua lag luam, 3rd tiam ADCs.

Concortis tab tom tshawb nrhiav ntau dua 20 qhov sib txawv ADC xaiv (ua ntej kho mob) nrog rau kev siv hauv oncology thiab tshaj. Thaum Lub Kaum Hli 19, 2015, Sorrento tshaj tawm txog kev tsim Levena Biopharma ua ib lub koom haum ywj pheej los muab kev lag luam ntau yam ntawm ADC cov kev pabcuam los ntawm kev pib ntawm ADC project los ntawm cGMP kev tsim khoom ntawm ADCs mus rau theem I / II kev tshawb fawb soj ntsuam. Yog xav paub ntxiv, thov mus saib www.levenabiopharma.com

SmartPharm Therapeutics, Inc

SmartPharm Therapeutics, Inc. ("SmartPharm"), ib lub koom haum ua lag luam tag nrho ntawm Sorrento Therapeutics, Inc. (Nasdaq: SRNE), yog lub tuam txhab kev loj hlob theem biopharmaceutical tsom mus rau tiam tom ntej, tsis yog-kab mob caj ces kho rau kev kho mob loj lossis tsis tshua muaj kab mob nrog lub zeem muag ntawm kev tsim "biology los ntawm sab hauv." SmartPharm tam sim no tab tom tsim ib qho tshiab, DNA-encoded monoclonal antibody los tiv thaiv kev kis tus kab mob SARS-CoV-2, tus kab mob uas ua rau COVID-19 raws li kev cog lus nrog Lub Chaw Haujlwm Saib Xyuas Kev Tshawb Fawb Txog Kev Tshawb Fawb ntawm US Department of Defense. SmartPharm tau pib ua haujlwm hauv 2018 thiab yog lub hauv paus hauv Cambridge, MA, USA.

Ark Animal Health

Ark Animal Health yog ib lub koom haum ua lag luam ntawm Sorrento. Ark tau tsim nyob rau xyoo 2014 los coj mus rau tus khub tsiaj ua lag luam cov kev daws teeb meem tshiab tawm los ntawm Sorrento tib neeg kev tshawb fawb thiab kev tsim kho kev ua ub no. Nws tau raug tsim los ua ib lub koom haum ywj pheej thiab muaj tus kheej txaus thaum nws mus txog theem kev lag luam (cov khoom npaj tau txais kev pom zoo FDA).

Ark's lead development program (ARK-001) yog ib koob tshuaj resiniferatoxin (RTX) sterile injectable solution. ARK-001 tau txais FDA CVM (Center for Veterinary Medicine) MUMS (me me / me hom) tsim los tswj kev mob qog noj ntshav hauv cov dev. Lwm cov haujlwm muaj xws li kev qhia ntxiv rau RTX hauv thaj chaw xws li mob pob qij txha hauv cov tsiaj ua ke, mob neuropathic hauv nees, thiab idiopathic cystitis hauv miv, nrog rau kev tshawb nrhiav kev txhim kho hauv thaj tsam ntawm cov kab mob sib kis lossis kev kho mob qog noj ntshav.

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