ʻO ka Sofusa® ʻO ka Lymphatic Delivery System (S-LDS) kahi ʻano hana lapaʻau hou i hoʻolālā ʻia e hāʻawi pololei i nā lāʻau injectable i loko o nā capillaries lymphatic a me systemic ma lalo o ka epidermis ma o ka microneedle proprietary a me ka ʻōnaehana microfluidics.
ʻO Sofusa Lymphatic Delivery System Overview. E kipa www.sofusa.com »
Hoʻonui ʻia ka hoʻopili ʻana
ʻAʻole e like me nā injections kuʻuna, hiki i ka Sofusa ("soft transdermal infusion) ka hoʻohana ʻana i ka absorption i loko o nā liʻiliʻi lymphatic a me nā capillaries systemic ma lalo o ka epidermis.
Nanotopography (hoʻonui nui ʻia)
ʻO ka nanotopography kiʻiʻoniʻoni lahilahi i hoʻohana ʻia i nā microneedles ka hopena i ka piʻi nui ʻana o ka absorption o nā molekala nui a me nā microneedles undraped.
ʻO ka hoʻopaʻa ʻana i loko o ka Lymphatic
I nā hiʻohiʻona pre-clinical i hoʻohālikelike ʻia me ka injection kuʻuna, ua hōʻike ʻo Sofusa i ka pane ʻana o ka lāʻau lapaʻau i hoʻonui ʻia me ka hoʻonui ʻana i nā konohiki lymphatic a me ka hōʻemi ʻana i ka ʻōnaehana.1.
(1) ʻIkepili ma ka faila - Nui nā haʻawina pre-clinical e pili ana i ka etanercept, trastuzumab, CTLA-4, PD-1, a me PD-L1