Pūnaehana Hoʻouna Lymphatic

« Hoʻi i ka Pipeline

ʻO ka Sofusa® ʻO ka Lymphatic Delivery System (S-LDS) kahi ʻano hana lapaʻau hou i hoʻolālā ʻia e hāʻawi pololei i nā lāʻau injectable i loko o nā capillaries lymphatic a me systemic ma lalo o ka epidermis ma o ka microneedle proprietary a me ka ʻōnaehana microfluidics.

ʻO Sofusa Lymphatic Delivery System Overview. E kipa www.sofusa.com »

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hoʻonui-absorption
 
Hoʻonui ʻia ka hoʻopili ʻana

ʻAʻole e like me nā injections kuʻuna, hiki i ka Sofusa ("soft transdermal infusion) ka hoʻohana ʻana i ka absorption i loko o nā liʻiliʻi lymphatic a me nā capillaries systemic ma lalo o ka epidermis.

nano-structured-microneedles
 
Nanotopography (hoʻonui nui ʻia)

ʻO ka nanotopography kiʻiʻoniʻoni lahilahi i hoʻohana ʻia i nā microneedles ka hopena i ka piʻi nui ʻana o ka absorption o nā molekala nui a me nā microneedles undraped.


ʻO ka hoʻopaʻa ʻana i loko o ka Lymphatic

I nā hiʻohiʻona pre-clinical i hoʻohālikelike ʻia me ka injection kuʻuna, ua hōʻike ʻo Sofusa i ka pane ʻana o ka lāʻau lapaʻau i hoʻonui ʻia me ka hoʻonui ʻana i nā konohiki lymphatic a me ka hōʻemi ʻana i ka ʻōnaehana.1.

(1) ʻIkepili ma ka faila - Nui nā haʻawina pre-clinical e pili ana i ka etanercept, trastuzumab, CTLA-4, PD-1, a me PD-L1