immunotherapy

"Koma zuwa Pipeline

G-MABTM library

Fasahar G-MAB ta mallaka ta Sorrento, wanda Dr. Ji ya ƙirƙira, ya dogara ne akan amfani da rubutun RNA don haɓaka madaidaitan yanki na antibody daga masu ba da gudummawa sama da 600. 

Bincike mai zurfi na bayanan DNA mai zurfi ya nuna cewa ɗakin karatu na G-MAB ya ƙunshi fiye da quadrillion 10 (10).16) daban-daban jerin antibody. Wannan ya sa ta zama ɗayan manyan ɗakunan karatu na rigakafin jikin mutum mafi girma a cikin masana'antar biopharmaceutical. Ya zuwa yanzu, Sorrento ya sami nasarar gano cikakken ƙwayoyin rigakafin ɗan adam akan sama da 100 masu alaƙa da babban tasirin cutar kancogenic, gami da PD-1, PD-L1, CD38, CD123, CD47, VEGFR2, da CCR2.

Matsakaicin nasarar gwajin da aka yi nasara (wanda aka bincika 100+ da suka dace da asibiti).

  • Babban bambancin (2 x 1016 daban-daban jerin antibody)
  • Fasaha ta mallaka (ƙarfin RNA don tsara ɗakin karatu)

Ƙarfin Ƙarfafawa:

  • cGMP kayan aiki
  • Cika / gama iyawa
  • Cikakken goyon bayan nazari