Masana'antar Shari'a (Antibodies, Cell Therapies)
Na zamani cGMP antibody da cell therapy masana'antu makaman dake a San Diego, CA, da farko an ƙera don zama Multi-samfuri makaman domin kerar da yawa tsarkakewa sunadaran da antibodies don amfani a matsayin therapeutics. Wurin da aka sake fasalin ya dace da buƙatun cGMP don kera Sabbin Magungunan Bincike, kuma yanzu ya haɗa da iyakoki don hanyoyin kwantar da hankali ta salula.
Cikawar Bioserv Aseptic da Kammala Kayan Aikin Kwangila
Yanzu wani ɓangare na ainihin ƙarfin Sorrento, Bioserv, ƙungiyar sabis na masana'antar kwangilar cGMP an samu kuma an haɗa su. Tare da kayan aiki / ɗakunan tsabta da kuma tsarin inganci masu girma, Bioserv yana ba da sabis na aseptic da marasa aikin cikawa / ƙarewa ciki har da lyophilization don ilimin kimiyyar halittu, masana'antun magunguna da na bincike, da lakabi / kitting da zafin jiki na tsawon lokaci mai sarrafawa, ajiyar sanyi da daskararre.
Camino Santa Fe Oncolytic Virus Facility
Wurin samar da ƙwayoyin cuta na Sorrento ya haɗa da haɓaka tsari da dakunan gwaje-gwaje na gwaji da kuma cGMP ɗakunan tsabta. Ayyukan da ke da tallafi sun haɗa da al'adun tantanin halitta, tsarkakewa, cikawa da ƙarewa gami da haɓaka ƙima da gwajin sarrafa inganci. Wurin yana da lasisi daga reshen Abinci da Magunguna na CA kuma ya sami nasarar kera abubuwan ƙwayoyi da samfuran magunguna don gwajin asibiti na farko, PHASE I da PHASE II.
ADC Conjugation, Payload da Linker Synthesis Facility
Sorrento yana sarrafa kayan aikin sa na cGMP don samar da Antibody Drug Conjugate (ADC) a Suzhou, China, a ƙarƙashin sunan alamar Levena Biopharma. Shafin yana aiki tun 2016 kuma yana iya tallafawa samar da cGMP na asibiti na masu haɗin magunguna da kuma haɗin kai na rigakafi. Tare da cikakken ƙarfin goyan bayan nazari da kayan aikin da aka tanadar don ɗaukar API mai ƙarfi (mai keɓewa), rukunin yanar gizon ya tallafawa batches na asibiti sama da 20 don gwaji na asibiti a duk duniya.
Cibiyar Nazarin Sofusa da Kera
Ƙwararrun masana'antu na SOFUSA a Atlanta, GA sun haɗa da ingantattun dabarun nanofabrication tare da haɗawa da gwajin abubuwan na'urar. Aikin yana iya tallafawa kera na'urori na al'ada don tallafawa duka karatun na yau da kullun da gwajin asibiti na Mataki na I da na II. Bugu da ƙari, cibiyar bincike na SOFUSA ita ce ƙananan ƙananan dabbobi masu aiki tare da fasahar fasaha na zamani (NIRF, IVIS, PET-CT) don kwatanta cikakken tasirin tasirin lymphatic dangane da alluran gargajiya da infusions.
